ISBN-10: 331917388X

ISBN-13: 9783319173887

This sensible consultant presents the reader with solutions to special clinically suitable questions concerning the assessment and administration of acute kidney damage (AKI). All elements of severe care nephrology are coated, from pathophysiology and prognosis to prevention and therapy. The questions thought of relate to quite a lot of concerns, reminiscent of: How do I diagnose AKI? How am i able to shield the kidney in scientific perform? How do I deal with sufferers with AKI? while should still I start up and the way do I practice renal alternative remedy (RTT)? which sort of RTT is most excellent for my sufferer? may still I supply particular food? as well as delivering functional instructions and remedy algorithms, the e-book contains calculators for non-stop RRT and anticoagulant dosing. The authors are across the world popular specialists within the fields of in depth Care drugs and Nephrology and all contributions are written in a transparent and concise sort and feature been peer reviewed. Acute Nephrology for the serious Care doctor will function a really important resource for intensivist internists, anesthesiologists and nephrologists all in favour of the administration and remedy of severely unwell sufferers vulnerable to or stricken by AKI.

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Extra resources for Acute Nephrology for the Critical Care Physician

Example text

Several studies in animal models of sepsis have demonstrated the role of TNF in the development of acute kidney injury: mice lacking a TNF receptor are resistant to endotoxin-induced acute kidney injury and TNF-receptor negative kidneys are resistant to endotoxin-induced damage when transplanted into TNF-positive mice [32]. In human sepsis, elevated serum levels of two soluble TNF-receptors are strongly associated with the development of acute kidney injury [35]. TNF is believed to induce apoptotic cell death through intracellular signaling.

2007;72(1):92–9. 5. Go AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351(13):1296–305. 6. Kerr M, Bray B, Medcalf J, O’Donoghue DJ, Matthews B. Estimating the financial cost of chronic kidney disease to the NHS in England. Nephrol Dial Transplant. 2012;27 Suppl 3: iii73–80. 7. The National Collaborating Centre for Chronic Conditions (UK). Chronic kidney disease: national clinical guideline for early identification and management in adults in primary and secondary care.

15. Jones J, Holmen J, De Graauw J, Jovanovich A, Thornton S, Chonchol M. Association of complete recovery from acute kidney injury with incident CKD stage 3 and all-cause mortality. Am J Kidney Dis. 2012;60(3):402–8. 3 Renal Outcomes After Acute Kidney Injury 37 16. Mammen C, Al Abbas A, Skippen P, et al. Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: a prospective cohort study. Am J Kidney Dis. 2012;59(4):523–30. 17. Siew ED, Peterson JF, Eden SK, et al.

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